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. 2017 Feb 2;12(2):e0171008. doi: 10.1371/journal.pone.0171008

Fig 2. Cell proliferation: The effects of different blood derivatives on cellular proliferation with MTS assay.

Fig 2

At 24 hours and 48 hours, corneal epithelial cells incubated with fetal bovine serum had significantly higher proliferative responses than those incubated in human peripheral serum, UltraGRO human platelet lysate (HPL), and PLTMax HPL. At 72 hours, there was no difference among these 4 products in 3% and 5% preparations. At 24, 48, and 72 hours, the proliferative responses showed no statistical difference between 3% and 5% blood derivative preparations. However, 10% preparation demonstrated poorer proliferative response compared to 3% and 5% preparations at all time points. FBS: fetal bovine serum, HPS: human peripheral serum. UltraGRO: Human platelet lysate from Helios pharmaceutical. PLTMax: Human platelet lysate from Mill Creek pharmaceutical. * indicated p <0.05. ** indicated p <0.01 compared to the control group that was without blood derivative in culture media.