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. 2017 Feb 2;12(2):e0171056. doi: 10.1371/journal.pone.0171056

Fig 6. Proposed reaction mechanism.

Fig 6

Reaction mechanism for the Friedel–Crafts alkylation catalyzed by SAM-dependent C-methyltransferases, CouO from Streptomyces rishiriensis and NovO from Streptomyces spheroides.