Table 2. Association between serum phosphorus and dementia subtypes.

Dementia subtypes			Quintile 1 Phosphorus ≤ 2.9mg/dL	Quintile 2 Phosphorus > 2.9 and ≤ 3.2 mg/dL	Quintile 3 Phosphorus > 3.2 and ≤ 3.5 mg/dL	Quintile 4 Phosphorus > 3.5 and ≤ 3.9 mg/dL	Quintile 5 Phosphorus> 3.9 mg/dL
Alzheimer’s	Overall	HR (CI)	1.07 (1.01, 1.13)	1	1.01 (0.95, 1.07)	1.03 (0.97, 1.10)	1.06 (0.98, 1.13)
	Age ≤ 60	HR (CI)	1.07 (0.77, 1.50)	1	1.37 (0.98, 1.90)	1.63 (1.19, 2.23)	1.59 (1.15, 2.20)
	Age > 60	HR (CI)	1.07 (1.01, 1.13)	1	1.00 (0.94, 1.06)	1.01 (0.95, 1.08)	1.04 (0.97, 1.12)
Vascular dementia	Overall	HR (CI)	1.09 (1.01, 1.19)	1	1.05 (0.98, 1.13)	1.05 (0.97, 1.13)	1.16 (1.07, 1.26)
	Age ≤ 60	HR (CI)	0.77 (0.57, 1.04)	1	1.15 (0.87, 1.52)	1.17 (0.89, 1.53)	1.41 (1.08, 1.85)
	Age > 60	HR (CI)	1.11 (1.03, 1.19)	1	1.05 (0.97, 1.13)	1.04 (0.96, 1.13)	1.14 (1.05, 1.24)
Dementia with Lewy body	Overall	HR (CI)	1.08 (0.94, 1.24)	1	0.96 (0.83, 1.11)	0.94 (0.81, 1.09)	0.98 (0.83, 1.16)
	Age ≤ 60	HR (CI)	2.18 (0.92, 5.15)	1	2.28 (0.94, 5.49)	3.38 (1.47, 7.77)	3.20 (1.36, 7.52)
	Age > 60	HR (CI)	1.05 (0.92, 1.21)	1	0.94 (0.81, 1.09)	0.89 (0.77, 1.04)	0.94 (0.79, 1.12)
Frontotemporal dementia	Overall	HR (CI)	0.94 (0.72, 1.24)	1	0.98 (0.74, 1.30)	0.92 (0.69, 1.23)	1.12 (0.82, 1.52)
	Age ≤ 60	HR (CI)	0.67 (0.34, 1.35)	1	1.17 (0.62, 2.22)	0.64 (0.30, 1.34)	0.89 (0.44, 1.82)
	Age > 60	HR (CI)	1.00 (0.74, 1.34)	1	0.94 (0.69, 1.29)	1.00 (0.73, 1.36)	1.20 (0.85, 1.68)

Abbreviations: HR, hazard ratio; CI, confidence interval.

Model adjusted for age, race, gender, diabetes mellitus, cardiovascular disease, peripheral artery disease, hypertension, atrial fibrillation, depression, liver cirrhosis, baseline eGFR, number of eGFR measurements and number of hospitalizations.

Quintile 2 (phosphorus >2.9 and ≤3.2 mg/dl) served as the reference group.