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. 2017 Feb 2;13(2):e1006153. doi: 10.1371/journal.ppat.1006153

Fig 1. Mouse sepsis model.

Fig 1

Female, 6–10 weeks old, C57BL/6NCRl mice (n = 5 for all groups except SE620Δpsm-mec and SE620psm-mec*, n = 10) were injected via the tail vein with 5 x 108 CFU of the indicated bacterial strains and monitored for disease development every 8 h for up to 120 h. (A,B) Survival curves; (C,D) CFU in blood at 12 h; (E,F) CFU in kidneys at 12 h. Statistical analysis is by Log-rank (Mantel-Cox) tests for survival curves, otherwise using 1-way ANOVA with Bonferroni post-tests. Error bars show ±SEM. N.S., not significant. Δpsm-mec, isogenic psm-mec deletion mutant; psm-mec*, psm-mec gene start codon mutant.