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Cytokine concentrations (A, CXCL1, B, IL-1β, C, TNF-α) were determined at 12 h post infection in the mouse sepsis model using commercial ELISA kits. Statistical analysis is by 1-way ANOVA with Bonferroni post-tests. Error bars show ±SEM. ****, P<0.0001. Δpsm-mec, isogenic psm-mec deletion mutant; psm-mec*, psm-mec gene start codon mutant.
