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. 2017 Feb 2;12(2):e0171583. doi: 10.1371/journal.pone.0171583

Table 1. The distributions of demographical characteristics in 1200 controls and 876 male patients with oral cancer.

Variable Controls (N = 1200) Patients (N = 876) p value
Age (yrs)
53.90 ± 10.02 54.80 ± 11.03 p = 0.06
Betel quid chewing
No 1001 (83.4%) 175 (20.0%)
Yes 199 (16.6%) 701 (80.0%) p <0.01*
Cigarette smoking
No 564 (47.0%) 92 (10.5%)
Yes 636 (53.0%) 784 (89.5%) p <0.01*
Alcohol drinking
No 963 (80.3%) 388 (44.3%)
Yes 237 (19.8%) 488 (55.7%) p <0.01*
Stage
I+II 435 (49.7%)
III+IV 441 (50.3%)
Tumor T status
T1+T2 512 (58.4%)
T3+T4 364 (41.6%)
Lymph node status
N0 597 (68.2%)
N1+N2+N3 279 (31.8%)
Metastasis
M0 868 (99.1%)
M1 8 (0.9%)
Cell differentiation
Well differentiated 141 (16.1%)
Moderately or poorly differentiated 735 (83.9%)

Mann-Whitney U test or Fisher’s exact test was used between healthy controls and patients with oral cancer.

* p value < 0.05 as statistically significant.