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. 2017 Jan 23;13(1):e1006147. doi: 10.1371/journal.ppat.1006147

Fig 9. QLT-0276 reduces oocyte numbers and affects their morphology in paired females.

Fig 9

Fluorescence microscopy of paired females with a focus on their ovaries. Females were treated for 3 days with DMSO (upper panel) or QLT-0276 (100 μM, lower panel) before staining with Hoechst 33342 (left) or anti-β-tubulin (middle). Merged images are shown right. Arrows indicate compact and rounded primary oocytes within the QLT-0276-treated group. iO, immature oogonia; mO, mature primary oocytes; scale bars: 50 μm.