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. Author manuscript; available in PMC: 2017 Oct 1.
Published in final edited form as: Mol Cancer Ther. 2016 Aug 5;15(10):2521–2529. doi: 10.1158/1535-7163.MCT-16-0258

Figure 1.

Figure 1

Derivation and analysis of tetO-KIF5B-RET transgenic mice. A, schematic representation of tetO-KIF5B-RET transgene. B, scheme for production of C/KR bitransgenic mice and induction of the KIF5B-RET transgene expression in the mouse lung type II epithelial cells. C, RT-PCR analysis of KIF5B-RET mRNA expression in various tissues in monotransgenic tetO-KIF5B-RET mouse and in C/KR bitransgenic mouse fed with Dox diet for 1 month. D, after induction with Dox diet for 1 month, cell lysates were prepared from lung tissues of CCSP-rtTA/tetO-KIF5B-RET (C/KR) bitransgenic or wildtype (W) mice. Immunoprecipitation-immunoblotting analysis of KR expression and phosphorylation was performed.

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