Grh binding is enriched in accessible, promoter-proximal chromatin. (A) Average FAIRE-seq signal from third instar imaginal wing discs across 5 kb regions centered on the set of Grh-binding sites maintained over embryonic development (top). Heat map of FAIRE-seq signal from imaginal wing discs ranked by average Grh ChIP-seq peak height (bottom). (B) Pie chart showing the genomic distribution of promoters (<1 kb upstream of TSS), upstream regions (1–3 kb upstream of TSS), exons, introns, untranslated regions (UTR) and intergenic regions (top). Pie charts showing the distribution of Grh ChIP-seq peaks from embryos, wing discs, or eye discs (below).