Figure 1.

Diazinon exposure altered the gut microbiome community structures in both (A) male and (B) female animals, as illustrated by the 3D PCoA plots based on the UniFrac distance metric and beta diversity (Red: controls; Blue: diazinon-treated animals); the hierarchical clustering analysis reveals that diazinon-treated mice and controls generally cluster in their own groups using the gut bacteria analyzed at the genus level (C: males; D: females); the jackknifed beta diversity via the unweighted pair group method with arithmetic mean (UPGMA) demonstrated that control and diazinon-treated male and female mice have distinct clustering patterns within each group (E: males; F: females), with the UPGMA distance tree constructed at a distance of 0.1.