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. 2016 May 20;125(2):198–206. doi: 10.1289/EHP202

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Diazinon exposure perturbed the metabolic profiles of fecal samples of mice, with 306 and 214 molecular features being significantly changed in (A) male and in (C) female animals, respectively (fold change > 1.5 and p < 0.05). Controls were separated from diazinon-treated mice in fecal metabolite profiles by PLS-DA (B: males; D: females). Two major neurotransmitters, taurine and glycine, were more significantly downregulated in male than female mice (E: taurine; F: glycine). Note: N.S., no statistical significance.