Table 2. Comparison of Inflammatory Markers Measured on Hospital day 0, 3, and 7 between Survivors and Non-Survivors.
| HD | Total | Survivors | Non-survivors | p value |
|---|---|---|---|---|
| PTX3 (ng/mL) | ||||
| 0 | 51.6 (14.3–197.6) | 36.5 (13.7–145.3) | 201.4 (56.9–268.6) | 0.008 |
| 3 | 12.7 (8.7–34.1) | 10.5 (8.5–17.3) | 66.4 (49.3–146.1) | 0.002 |
| 7 | 8.9 (7.8–13.5) | 8.8 (7.7–11.8) | 49.7 (25.8–163.6) | 0.003 |
| Procalcitonin (ng/mL) | ||||
| 0 | 9.9 (0.6–30.6) | 7.8 (0.3–30.6) | 17.4 (9.7–33.4) | 0.114 |
| 3 | 8.2 (0.2–12.7) | 5.2 (0.1–12.9) | 4.5 (0.3–21.7) | 0.909 |
| 7 | 0.6 (0.1–2.1) | 0.6 (0.1–1.8) | 1.6 (0.6–19.1) | 0.113 |
| CRP (mg/L) | ||||
| 0 | 106.1 (42.3–174.2) | 106.1 (35.4–169.2) | 117.0 (55.6–201.5) | 0.723 |
| 3 | 64.1 (29.6–156.7) | 64.1 (27.7–156.7) | 58.8 (45.9–236.1) | 0.634 |
| 7 | 36.3 (12.7–76.9) | 35.3 (12.3–70.7) | 102.5 (47.0–172.6) | 0.004 |
| DNI (%) | ||||
| 0 | 6.1 (1.9–13.6) | 5.1 (1.3–10.0) | 14.3 (5.8–50.1) | 0.003 |
| 3 | 0.8 (0.0–2.9) | 0.8 (0.0–2.1) | 2.3 (0.4–4.1) | 0.224 |
| 7 | 1.6 (0.1–3.0) | 1.2 (0.0–3.0) | 1.8 (1.7–4.7) | 0.145 |
PTX3, pentraxin 3; CRP, C-reactive protein; DNI, delta neutrophil index; HD, hospital day.
Values are presented as the median (interquartile range). The number of total participants who received the measurement of above four inflammatory markers were 83, 78, and 76 at HD 0, 3, and 7, respectively. In survivors, the inflammatory markers were measured in 67 patients at all HD 0, 3, and 7. In non-survivors, the number of patient who received the measurement of the inflammatory markers were 16, 11, and 9 at HD 0, 3, and 7, respectively.