Table 3.

GLMM outcomes with protocol violation as dependent variable and opinions and conditions as independent variables

BeSt				IMPROVED
Opinions	OR	95 % CI	p value	OR	95 % CI	p value
Not satisfied with treatment effect	1.36	1.08–1.71	0.010	0.59	0.49–0.72	<0.001
Disagreement with DAS (felt overestimation of actual disease activity)	2.26	1.84–2.78	<0.001	5.97	4.82–7.40	<0.001
Disagreement with DAS (felt underestimation of actual disease activity)	2.82	2.08–3.81	<0.001	1.44	1.01–2.07	0.047
Not satisfied next treatment step	2.77	2.34–3.28	<0.001	3.53	2.84–4.37	<0.001
Conditions
1	1.00	0.85–1.18	0.993	3.1	2.73–3.52	<0.001
2	1.03	0.80–1.33	0.826	1.74	1.42–2.14	<0.001
3	1.04	0.89–1.22	0.629	2.03	1.80–2.29	<0.001
4	1.34	1.14–1.57	<0.001	2.18	1.85–2.56	<0.001
5	1.36	1.00–1.86	0.050	0.89	0.64–1.24	0.493

DAS disease activity score, OR odds ratio, CI confidence interval