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. Author manuscript; available in PMC: 2018 Feb 1.
Published in final edited form as: Genes Brain Behav. 2016 Oct 3;16(2):250–259. doi: 10.1111/gbb.12327

Figure 7. Thy1-GFP highlights structural deficits in the adult dentate gyrus.

Figure 7

Staining shows mossy fiber projections in 4 month old control Thy1-GFP/+;Tubb2b+/+ (A) and Thy1-GFP/+;Tubb2bbrdp/+ (B) animals in the CA3 region. Note that in the control animals there is both a suprapyramidal bundle (SPB, white brackets) and an infrapyramidal bundle (IPB, yellow arrow heads). In contrast, mossy fibers appear less dense and there is a lack of separation between the SPB and IPB in the Tubb2bbrdp/+ animals (asterisks).