Table 1. Baseline clinical characteristics of 379 patients with lung SCC.
| Parameters | Never-smoker (n = 19) | Ever-smoker (n = 360) | P value |
|---|---|---|---|
| Age, yr | 67 (57–73) | 70 (65–75) | 0.055* |
| Male | 9 (47.4) | 349 (96.9) | < 0.001† |
| BMI, kg/m2 | 21.9 (21.0–24.3) | 22.8 (20.6–25.0) | 0.644* |
| Smoking status | |||
| Pack-years | 0 | 40 (30–50) | - |
| Final stage | 0.618† | ||
| I | 5 (26.4) | 91 (25.2) | |
| II | 1 (5.3) | 68 (18.9) | |
| III | 6 (31.6) | 114 (31.7) | |
| IV | 7 (36.8) | 87 (24.2) | |
| Tumor size, cm | 3.9 (2.9–4.4) | 4.0 (3.0–5.7) | 0.552* |
| SUVmax | 15.0 (11.6–17.0) | 16.0 (11.5–20.8) | 0.193* |
| CEA | 2.9 (1.8–8.5) | 2.1 (1.5–3.9) | 0.230* |
| CYFRA 21-1 | 3.8 (2.4–6.1) | 4.5 (2.5–10.2) | 0.517* |
| NSE | 19.9 (13.0–36.7) | 17.5 (13.9–26.1) | 0.571* |
Values are presented as median (IQR) or number (%).
SCC = squamous cell carcinoma, BMI = body mass index, SUVmax = maximum standardized uptake value, CEA = carcinoembryonic antigen, CYFRA 21-1 = cytokeratin 19-fragments, NSE = neuron specific enolase, IQR = interquartile range.
*P value from Mann-Whitney test; †P value from χ2 test.