Table 5. Correlation analyses of various parameters and FeNO levels.
Parameters | FeNO | |
---|---|---|
r | P | |
ACOS severity | 0.695 | < 0.001 |
FEV1%pred, % | −0.777 | < 0.001 |
FEV1/FVC, % | −0.430 | < 0.001 |
IC/TLC, % | −0.304 | < 0.001 |
RV/TLC, % | 0.289 | 0.001 |
pH | −0.466 | < 0.001 |
PaO2, mmHg | −0.328 | < 0.001 |
PaCO2, mmHg | 0.468 | < 0.001 |
Total serum IgE level, IU/mL | 0.726 | < 0.001 |
Induced sputum EOS% | 0.578 | < 0.001 |
Plasma SP-A | 0.215 | 0.015 |
Plasma sRAGE | −0.354 | < 0.001 |
Sputum MPO | 0.531 | < 0.001 |
Sputum NGAL, mg/L | 0.590 | < 0.001 |
ACT scores | −0.603 | < 0.001 |
CAT scores | 0.647 | < 0.001 |
ACOS = asthma-chronic obstructive pulmonary disease overlap syndrome, COPD = chronic obstructive pulmonary disease, ACT = Asthma Control Test, CAT = COPD Assessment Test, MPO = sputum myeloperoxidase, NGAL = sputum neutrophil gelatinase-associated lipocalin, sRAGE = plasma soluble receptor for advanced glycation end products, SP-A = plasma surfactant protein A, EOS = induced sputum eosinophil counts, FEV1%pred = percentage of forced expiratory volume in 1 second (FEV1) to predicted value, FEV1/FVC = the ratio of FEV1 to forced vital capacity, IC/TLC = ratio of inspiratory capacity to total lung capacity, RV/TLC = ratio of residual volume to total lung capacity, FeNO = fractional exhaled nitric oxide, PaO2 = arterial oxygen partial pressure, PaCO2 = partial pressure of carbon dioxide in artery, IgE = immunoglobulin E.