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. 2017 Jan 27;8:14246. doi: 10.1038/ncomms14246

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Copyright © 2017, The Author(s)

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Rates of spontaneous mutations conferring Rif-R of the M. smegmatis ΔnucS complemented with wild-type nucS_TB (ΔnucS/nucS_TB; red) or containing each of the nine polymorphisms indicated (blue). Relative increases in mutation rates with respect to the control strain (ΔnucS/nucS_TB; set to 1) are shown inside the column. Error bars represent 95% confidence intervals (n=20). Asterisks denote statistical significance (Likelihood ratio test under Luria-Delbruck model, Bonferroni corrected; ***P<0.001; **P<0.005). Mutation rate: mutations per cell per generation.