Table 3. Comparison of TSH level according to perinatal factors.
| Variable | No. (%) | TSH | P-value | lnTSH | P-value |
|---|---|---|---|---|---|
| Sex | |||||
| Male | 373 (52.9) | 3.85±1.90 | 1.22±0.52 | ||
| Female | 332 (47.1) | 3.69±1.92 | 0.257 | 1.17±0.53 | 0.200 |
| Multiple delivery | |||||
| Singleton | 679 (96.3) | 3.75±1.89 | 1.19±0.52 | ||
| Twin | 26 (3.7) | 4.57±2.37 | 0.032 | 1.42±0.42 | 0.026 |
| Birth order | |||||
| 1st baby | 433 (61.4) | 3.89±1.92 | 1.24±0.49 | ||
| 2nd or later baby | 272 (38.6) | 3.60±1.88 | 0.054 | 1.14±0.56 | 0.011 |
| Apgar score at 1 min | |||||
| <7 | 18 (2.6) | 3.56±1.51 | 1.17±0.48 | ||
| ≥7 | 687 (97.4) | 3.78±1.92 | 0.629 | 1.20±0.52 | 0.811 |
| Apgar score at 5 min | |||||
| 7, 8 | 65 (9.2) | 4.12±1.93 | 1.30±0.50 | ||
| 9, 10 | 640 (90.8) | 3.74±1.91 | 0.126 | 1.19±0.52 | 0.099 |
| Delivery type | |||||
| Spontaneous | 571 (81.0) | 3.72±1.91 | 1.18±0.53 | ||
| Vacuum assisted | 134 (19.0) | 4.01±1.91 | 0.111 | 1.28±0.49 | 0.048 |
| Labor type | |||||
| Spontaneous | 218 (30.9) | 3.60±1.79 | 1.15±0.52 | ||
| Induced | 487 (69.1) | 3.85±1.96 | 0.104 | 1.22±0.52 | 0.115 |
| Maternal diabetes | |||||
| Normal | 653 (92.6) | 3.75±1.89 | 1.19±0.52 | ||
| GDM/DM | 52 (7.4) | 4.14±2.10 | 0.149 | 1.29±0.53 | 0.191 |
| Maternal hypertension | |||||
| Normal | 688 (97.6) | 3.77±1.92 | 1.20±0.52 | ||
| PIH | 17 (2.4) | 4.00±1.64 | 0.625 | 1.30±0.45 | 0.439 |
| Maternal thyroid disease | |||||
| Normal | 646 (91.6) | 3.76±1.94 | 1.19±0.53 | ||
| Hypothyroidisma) | 52 (7.4) | 3.98±1.70 | 0.439 | 1.28±0.47 | 0.245 |
| Hyperthyroidisma) | 7 (1.0) | 3.71±1.02 | 0.950 | 1.28±0.29 | 0.675 |
| Maternal medication | |||||
| None | 587 (83.3) | 3.78±1.92 | 1.20±0.52 | ||
| Insulinb) | 22 (3.1) | 3.79±2.23 | 0.969 | 1.16±0.62 | 0.693 |
| L-thyroxineb) | 41 (5.8) | 4.07±1.78 | 0.341 | 1.31±0.46 | 0.205 |
| Steroidb) | 2 (0.0) | 2.55±0.35 | 0.367 | 0.93±0.14 | 0.461 |
Values are presented as mean±standard deviation unless otherwise indicated.
TSH, thyroid stimulating hormone; lnTSH, log transformed TSH; GDM, gestational diabetes mellitus; DM, diabetes mellitus; PIH, pregnancy induced hypertension.
a)Maternal thyroid diseases in comparison with normal thyroid function. b)Maternal medication in comparison with no medication.