Table 1.
Patient Demographics, Indications for Surgery and Concurrent Procedures
| Control | Surgically Treated Glaucoma |
Medically Treated Glaucoma |
Total | P* | |
|---|---|---|---|---|---|
| No. DMEK/ eye | 60 | 34 | 14 | 108 | |
| Age (mean ± SD) (year) | 72.2±10.3 | 69.1±16.4 | 74.1±7.1 | 71.5±12.3 | 0.78 |
| Sex, N (%) | 0.59 | ||||
| Female | 34 (57%) | 19 (56%) | 10 (71%) | 63 (58%) | |
| Male | 26 (43%) | 15 (44%) | 4 (29%) | 45 (42%) | |
| Mean Follow-up (range, month) | 9.8±7.5 (0.3 to 27.6) | 8.4±6.9 (1.1 to 26.7) | 11.7±7.6 (0.3 to 26.7) | 9.7±7.3 (0.3 to 26.7) | 0.34 |
| Surgical indication. N, (%) | <0.0001† | ||||
| FECD | 49 (81.7) | 2 (5.9) | 8 (57.1) | 59 (54.6) | |
| PBK | 5 (8.3) | 22 (64.7) | 3 (21.4) | 30 (27.8) | |
| PK failure | 2 (3.3) | 2 (5.9) | 2 (14.3) | 6 (5.5) | |
| DSEK failure | 2 (3.3) | 7 (20.6) | 0(0) | 9 (8.3) | |
| DMEK failure | 0 (0) | 0 (0) | 1 (7.1) | 1 (0.9) | |
| Endothelitis | 2 (3.3) | 1 (2.9) | 0(0) | 3 (2.8) | |
| Previous vitrectomy | 3 (5) | 4 (11.8) | 1 (7.1) | 8 (7.4) | 0.38 |
| Lens status, N (%) | 0.0316‡ | ||||
| PCIOL | 39 (65) | 30 (88.2) | 10 (71.4) | 79 (73.1) | |
| Iris fixated IOL | 1 (1.7) | 1 (2.9) | 1(7.1) | 3 (2.8) | |
| Phakic | 20 (33.3) | 3 (8.8) | 3 (21.4) | 26 (24.1) | |
| Concurrent procedures, N (%) | |||||
| Cataract extraction with PCIOL | 18 (30) | 2 (5.9) | 3 (21.4) | 23 (21.3) | |
| Trimming of glaucoma drainage tube | 0 (0) | 16 (47) | 0 (0) | 16 (14.8) | |
| Lysis of irido-corneal adhesions | 3 (5) | 12 (35.3) | 2 (14.3) | 17 (15.7) | |
| Anterior vitrectomy | 0 (0) | 4 (11.8) | 0 (0) | 4 (3.7) | |
| Retrocorneal membrane peel | 3 (5) | 6 (17.6) | 1 (7.1) | 10 (9.3) | |
| Number of concurrent procedures, n (%) | 0.007§ | ||||
| 1 | 20 (33.3) | 13 (38.2) | 4 (28.6) | 37 (34.3) | |
| 2 | 2 (3.3) | 2 (5.9) | 1 (7.1) | 5 (4.6) | |
| 3 | 0 (0) | 8 (23.5) | 0 (0) | 8 (7.4) | |
| ≥2 | 2 (3.3) | 10 (29.4) | 1 (7.1) | 13 (12) |
DMEK, Descemet membrane endothelial keratoplasty; PBK, bullous keratopathy; FECD, Fuchs endothelial corneal dystrophy; PCIOL, posterior chamber intraocular lens; PK, penetrating keratoplasty.
†
Comparing FECD, PBK and Failed corneal transplant.
‡
Comparing PCIOL, Iris fixated and lens status.
§
Comparing ≤1 to ≥2 previous corneal transplants.
*
Fisher´s exact test.