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. Author manuscript; available in PMC: 2017 Nov 15.
Published in final edited form as: Cancer Res. 2016 Sep 2;76(22):6669–6679. doi: 10.1158/0008-5472.CAN-16-0571

Table 1.

Absorbed Radiation Doses

Tissue 2H7C825 CC49C825 T:N ratios for 2H7-C825 T:N ratios for CC49-C825
Blood 0.363 0.236 21.43 1.60
Lung 2.44 1.92 3.19 5.08
Liver 1.41 1.08 5.52 2.86
Spleen 1.51 1.1 5.15 2.91
Stomach 0.09 0.098 86.44 0.26
Kidneys 0.313 0.25 24.86 0.66
Small Intestine 0.101 0.122 77.03 0.32
Large Intestine 0.254 0.227 30.63 0.60
Muscle 0.205 0.125 37.95 0.33
Femur 0.069 0.112 112.75 0.30
Tail 0.121 0.094 64.30 0.25
Carcass 0.267 0.051 29.14 0.13
Tumor 7.78 0.378 1.00 1.00

Absorbed Dose/μCi

The methods are those described by Hui et al (Hui, TE, Fisher DR, Kuhn JA, Williams LE, Nourigat C, Badger CC, Beatty BG, Beatty JD. A Mouse Model for Calculating Cross-Organ Beta Doses from 90Y-Labeled Immunoconjugates. Cancer 73(3Suppl):951–957, 1994). This method takes into account the beta particle absorbed fractions for small organs. The results are given as radiation absorbed dose (centigray) per unit administered activity (per microcurie).