Figure 2. Effect of cisplatin and PFT-µ on neuronal precursors cells in the brain.
Animals were treated with cisplatin and PFT-µ for two 5-day cycles. (A, F) PBS-treated animals. (B, G) Cisplatin-treated animals. (C, H) PFT-µ–treated animals. (D, I) PFT-µ/cisplatin-treated animals. DCX+ neuronal precursors were observed in the (A–D) DG of the hippocampus and (F–I) SVZ. (A’–D’) 40× magnification of the DG tip. DCX+ cells were counted in the (E) DG and the (J) SVZ.