Table 1.

Effect of cisplatin on the inflammatory response in the brain

Region	Gene	Saline	Cisplatin
24h post-treatment
Hippocampus	IL-1β	1.00 (0.10)	0.75 (0.05)*
	IL-6	1.00 (0.12)	1.15 (0.11)
	TNFα	1.00 (0.13)	0.80 (0.08)
	GFAP	1.00 (0.06)	0.87 (0.03)*
	CD11b	1.00 (0.05)	0.86 (0.04)*
Prefrontal Cortex	IL-1β	1.00 (0.16)	0.97 (0.09)
	IL-6	1.00 (0.06)	0.91 (0.07)
	TNFα	1.00 (0.37)	0.73 (0.11)
	GFAP	1.00 (0.06)	0.81 (0.01)*
	CD11b	1.00 (0.05)	0.80 (0.17)
7d post-treatment
Hippocampus	IL-1β	1.00 (0.22)	1.06 (0.25)
	IL-6	1.00 (0.30)	1.44 (0.28)
	TNFα	1.00 (0.07)	0.76 (0.05)*
	GFAP	1.00 (0.10)	1.03 (0.14)
	CD11b	1.00 (0.15)	1.03 (0.14)
Prefrontal Cortex	IL-1β	1.00 (0.08)	0.88 (0.13)
	IL-6	1.00 (0.13)	1.15 (0.06)
	TNFα	1.00 (0.18)	1.07 (0.30)
	GFAP	1.00 (0.03)	1.20 (0.24)
	CD11b	1.00 (0.04)	1.02 (0.10)