Table 1.
Regions of increased BOLD response in the HCB > LCB contrast, and correlations with overweight/obese measures (N = 24). No significant findings were present in the LCB > HCB contrast, and no correlations were observed with YFAS scores
| # voxels | Localization | BA | x (mm) | y (mm) | z (mm) | Max z |
|---|---|---|---|---|---|---|
| High calorie beverage (HCB) > Low calorie beverage (LCB) | ||||||
| 8736 | Bilateral Cerebellum | - | −16 | −68 | −54 | 4.61 |
| 4388 | Bilateral IFG/OFC/Bilateral Nucleus Accumbens/Right Amygdala |
10/47 | −36 | 62 | 4 | 4.31 |
| 1688 | Medial Superior Frontal Gyrus/Supplemental Motor Area/Right Middle Frontal Gyrus |
6 | 10 | 16 | 62 | 3.97 |
| 1576 | Right Frontal Pole/Lateral OFC | 10/46 | 48 | 44 | 16 | 4.04 |
| 1338 | Left Temporal Pole/Superior Temporal Gyrus | 221/22 | −50 | 20 | −28 | 4.16 |
| 1107 | Right Angular Gyrus/Inferior Parietal Lobe | 40 | 56 | −54 | 42 | 3.58 |
| 507 | Right Occipital Pole | 18 | 28 | −100 | −12 | 3.48 |
| Body mass index (BMI) | ||||||
| 735 | Right Postcentral gyrus/Central Operculum | 43 | 60 | −4 | 6 | 3.61 |
| Insulin Resistance (HOMA-IR) | ||||||
| 3814 | Bilateral Cerebellum | - | −2 | −52 | −26 | 3.89 |
| 1689 | Right Middle/Superior Temporal Gyrus | 20/21 | 66 | −22 | −16 | 3.5 |
| 1541 | Left Middle/Superior Temporal Gyrus | 20/21 | −60 | −42 | −10 | 3.77 |
| 1288 | Right Lateral Occipital Cortex | 39 | 62 | −50 | 28 | 3.51 |
| 1075 | Left Orbitofrontal Cortex | 47 | −48 | 36 | −12 | 3.24 |
| 729 | Left Superior Lateral Occipital Cortex/Superior Parietal Lobe |
7/39 | −30 | −66 | 52 | 2.99 |
The HCB > LCB map was corrected for multiple comparisons using a voxelwise threshold of 2.3 and a cluster level threshold of p < 0.05. Correlation maps (i.e., BMI and insulin resistance) were corrected for multiple comparisons using cluster-based thresholding (voxel z > 1.96, cluster p < 0.05)