Figure 3.

Effects of CV‐B4 on thymus integrity. The thymuses of six mice (three offspring born to each of two dams) of each experimental condition [oral virus inoculation at day 10 gestation (G) or 17G, and in the absence of inoculation] were subjected to histological examination at different post‐inoculation (p.i.) times (day 17G and days 0 and 5 from birth). No histopathological change was observed in all examined sections. Representative sections from a negative control thymus (a) and a thymus stemming from an intraperitoneal inoculation of CV‐B4 E2 at day 10G. (b) Both sampled at day 5 from birth, and examined after haematoxylin and eosin staining. Gr × 400. [Colour figure can be viewed at wileyonlinelibrary.com]