Table 3.
Regional volume means (SEM) by group and subgroup for the two primary regions of interest (ROIs) and the 11 exploratory regions of interest (ROI). Volumes (mm3) were corrected for intracranial volume, age and sex. No significant differences were seen in either group analysis (type 1 diabetes vs control or those with diabetic ketoacidosis (DKA+) or without (DKA−) (p>.05).
| ROI (*a priori) | Control | Type 1 diabetes | DKA− | DKA+ |
|---|---|---|---|---|
| n | 25 | 42 | 30 | 12 |
| Hippocampus* | 3968 (60) | 3914 (46) | 3897 (50) | 3936 (80) |
| Thalamus* | 7201 (78) | 7247 (60) | 7269 (71) | 7177 (113) |
| Accumbens | 688 (14) | 690 (11) | 672 (12) | 741 (20) |
| Amygdala | 1642 (32) | 1646 (25) | 1634 (29) | 1682 (46) |
| Brainstem | 18861 (253) | 18958 (195) | 18808 (233) | 19239 (372) |
| Caudate | 3937 (75) | 4030 (58) | 4045 (73) | 4006 (117) |
| Cerebellar Gray Matter | 53070 (706) | 52499 (544) | 52243 (650) | 53163 (1039) |
| Cerebellar White Matter | 14912 (236) | 14900 (181) | 14901 (241) | 14702 (385) |
| Corpus Callosum | 2867 (71) | 2920 (55) | 2946 (60) | 2827 (96) |
| Cortical Gray Matter | 537857 (4382) | 537452 (3374) | 540500 (3753) | 534448 (6002) |
| Cortical White Matter | 398693 (3213) | 398840 (2473) | 398005 (2951) | 401389 (4719) |
| Pallidum | 1711 (41) | 1737 (32) | 1702 (36) | 1841 (58) |
| Putamen | 6204 (126) | 6118 (97) | 6002 (118) | 6413 (188) |