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. 2017 Jan 30;8:14287. doi: 10.1038/ncomms14287

Figure 10. The mechano-sensing pathway influences the mammary clock in vivo.

Figure 10

(a) IF staining of pMLC expression in either 3-month or 24-month-old mammary gland tissue. N=3 animals, scale bar=50 μm. (b) Representative PER2::Luc bioluminescent traces of mammary tissue explants from 3-month or 24-month-old mice, treated with Y-27632 (100 μM, black arrow). Red, Y-27632 treatment; black, control treatment. Fold change of amplitude was quantified based on first peak following the treatment. Student's t-test, mean±s.e.m., ***P<0.001. N=3 animals.