Table 3a. Association results of the nominally significant SNPs in the human study.
Gene | SNP | Chr. | Position (GRCh38) |
‘No symptoms' vs ‘Anxiety only' |
||
---|---|---|---|---|---|---|
OR (95% CI) | P-value | q-value | ||||
GABRR1 | rs9342185 | 6 | 89204419 | 0.44 (0.25–0.78) | 0.005 | 0.215 |
GABRR1 | rs4707529 | 6 | 89208843 | 0.47 (0.26–0.86) | 0.015 | 0.241 |
GABRR1 | rs7758893 | 6 | 89206922 | 0.53 (0.30–0.92) | 0.025 | 0.241 |
GABRR1 | rs453503 | 6 | 89190880 | 0.52 (0.29–0.93) | 0.028 | 0.241 |
NOTCH1 | rs11145770 | 9 | 136532614 | 1.79 (1.10–2.89) | 0.018 | 0.241 |
Abbreviations: 95% CI, 95% confidence interval; OR, odds ratio; SNP, single-nucleotide polymorphism.
False discovery rate q-value <0.05.
The full table of results is presented in Supplementary Table 3.