Table 3b. Association results of the nominally significant SNPs in the human study.
| Gene | SNP | Chr. | Position (GRCh38) |
‘No symptoms' vs ‘Comorbid symptoms' |
||
|---|---|---|---|---|---|---|
| OR (95% CI) | P-value | q-value | ||||
| NOTCH1 | rs11145770 | 9 | 136532614 | 2.21 (1.35–3.61) | 0.002 | 0.043a |
| NOTCH1 | rs3013302 | 9 | 136537422 | 2.15 (1.32–3.49) | 0.002 | 0.043a |
| NOTCH1 | rs13301342 | 9 | 136499893 | 0.36 (0.16–0.77) | 0.009 | 0.097 |
| NOTCH1 | rs13290979 | 9 | 136531182 | 1.92 (1.18–3.15) | 0.009 | 0.097 |
Abbreviations: 95% CI, 95% confidence interval; OR, odds ratio; SNP, single-nucleotide polymorphism.
a
False discovery rate q-value <0.05.
The full table of results is presented in Supplementary Table 3.