Table 3. The interaction effect of group by composite cognitive score and neuroanatomical measures for each molecular parameter.
| Outcome variables | F (ηp2) |
|||||||
|---|---|---|---|---|---|---|---|---|
| CGG | AR | FMR1 mRNA | CpG 1 | CpG 2 | CpG 6/7 | CpG 8/9 | CpG 10–12 | |
| Prosaccade response time | 0.235 (0.014) | 3.038 (0.160) | 1.418 (0.081) | 0.416 (0.025) | 0.983 (0.058) | 2.535 (0.133) | 0.923 (0.053) | 0.556 (0.033) |
| Prosaccade error score | 15.533 (0.485) | 0.218 (0.013) | 1.803 (0.101) | 0.185 (0.011) | 0.691 (0.041) | 1.703 (0.094) | 2.108 (0.113) | 0.855 (0.049) |
| Executive function score | 6.620 (0.286) | 1.914 (0.107) | 1.077 (0.063) | 0.017 (0.001) | 1.168 (0.068) | 1.905 (0.104) | 1.309 (0.074) | 2.394 (0.127) |
| White matter hypointensities | 0.421 (0.025) | 1.905 (0.104) | 2.224 (0.122) | 2.125 (0.114) | 0.595 (0.036) | 3.080 (0.157) | 1.664 (0.092) | 0.580 (0.034) |
| Left middle frontal gyrus | 1.692 (0.093) | 1.012 (0.059) | 0.386 (0.024) | 0.032 (0.002) | 3.241 (0.168) | 8.131 (0.330) | 6.061 (0.269) | 6.088 (0.270) |
| Right middle frontal gyrus | 0.374 (0.022) | 0.549 (0.033) | 1.069 (0.063) | 0.253 (0.015) | 0.118 (0.007) | 1.405 (0.078) | 5.600 (0.253) | 1.803 (0.099) |
| Left superior frontal gyrus | 0.101 (0.006) | 0.319 (0.020) | 1.294 (0.075) | 0.701 (0.041) | 1.050 (0.062) | 3.033 (0.155) | 3.532 (0.176) | 2.678 (0.140) |
| Right superior frontal gyrus | 0.072 (0.004) | 0.767 (0.046) | 0.853 (0.051) | 0.797 (0.046) | 0.896 (0.053) | 3.497 (0.175) | 4.596 (0.218) | 1.790 (0.098) |
| Left inferior parietal gyrus | 0.035 (0.002) | 0.855 (0.051) | 1.134 (0.066) | 0.835 (0.048) | 0.129 (0.008) | 5.031 (0.234) | 2.717 (0.141) | 1.604 (0.089) |
| Right inferior parietal gyrus | 0.045 (0.003) | 0.477 (0.029) | 1.614 (0.092) | 0.177 (0.011) | 0.059 (0.004) | 0.372 (0.022) | 0.120 (0.007) | 0.303 (0.018) |
Abbreviations: ηp2, partial eta squared; AR, activation ratio; F, F-test statistic; FMR1, Fragile X mental retardation 1.
Note: Figures in bold indicate that P<0.05.