Table 3. Variables associated with amygdala levels of phospho-GluA1-Ser831.
| Variables | Amygdala levels of phospho-GluA1-Ser831 | P-value | ||
|---|---|---|---|---|
| Univariate analysisa | ||||
| Gender | Mean (s.e.) | |||
| Female | 103 (3.6) | |||
| Male | 117.4 (4.5) | 0.02a | ||
| AEDs regimen | ||||
| Monotherapy | 114 (5.0) | |||
| Two AEDs or more | 109 (3.9) | 0.51a | ||
| Phenobarbital treatment | ||||
| No | 111.7 (3.8) | |||
| Yes | 105.4 (4.9) | 0.32a | ||
| B | r | r2 | P-value | |
| Univariate linear regressions | ||||
| Monthly seizure frequency | −0.71 | 0.21 | 0.05 | 0.26b |
| Serum glucose | −0.19 | 0.32 | 0.10 | 0.12b |
| Storage time of samples (months) | 0.36 | 0.19 | 0.04 | 0.30b |
| Dexamethasone dose (mg kg−1) | −145.6 | 0.69 | 0.48 | 0.00002b |
| Multiple linear regression | ||||
| Constant | 134.8 | <0.00001 | ||
| Female | −0.90 | 0.85 | ||
| Serum glucose | −0.10 | 0.33 | ||
| Dexamethasone dose (mg kg−1) | −131.1 | 0.0003 | ||
| 0.73 | 0.53 | 0.001c | ||
Abbreviation: AEDs, antiepileptic drugs.
Univariate analysis by Student's t-test;
Univariate analysis by linear regression;
Level of significance for the multiple linear regression model.