Table 2. Baseline lipid profile of participants with and without EDS developed during follow-up.

Lipid and lipoprotein profile	Without EDS	With EDS	P
Conventional lipid measure
Total cholesterol, mg dl−1	193.5 (34.3)	192.8 (34.1)	0.02
LDL cholesterol, mg dl−1	118.2 (30.9)	115.7 (30.8)	0.003
HDL cholesterol, mg dl−1a	48 (40–58)	49 (41–60)	0.52
Non-HDL cholesterol, mg dl−1	143.0 (34.0)	140.9 (34.2)	0.01
Triglycerides, mg dl−1a	108 (77–155)	111 (77–160)	0.79
Total/HDL cholesterol ratio	4.08 (1.17)	3.96 (1.15)	0.04
LDL/HDL cholesterol ratio	2.52 (0.93)	2.41 (0.91)	0.01
Lipoprotein particle concentration
VLDL-P, nmol l−1
Totala	62.1 (39.9–87.9)	63.2 (40.2–88.4)	0.58
Largea	2.4 (0.8–6.1)	2.6 (0.9–6.5)	0.70
Mediuma	23.4 (12.1–40.6)	23.8 (11.9–39.5)	0.60
Smalla	31.5 (19.6–44.8)	32.7 (20.4–45.4)	0.74
IDL-P, nmol l−1a	102 (50–176)	103 (51–174)	0.04
LDL-P, nmol l−1
Total	1131 (304)	1110 (317)	0.06
Large	584 (252)	602 (259)	0.89
Small	547 (374)	508 (375)	0.09
HDL-P, μmol l−1
Total	33.7 (6.5)	34.6 (6.7)	0.18
Largea	5.0 (3.3–7.6)	5.3 (3.6–8.2)	0.14
Mediuma	12.2 (8.3–16.6)	12.8 (8.9–17.5)	0.62
Small	14.9 (5.5)	14.6 (5.8)	0.87
Lipoprotein particle size, nm
VLDL-P	48.2 (7.7)	48.5 (7.8)	0.93
LDL-P	20.7 (0.5)	20.8 (0.5)	0.75
HDL-P	9.2 (0.5)	9.3 (0.5)	0.10

Abbreviations: EDS, elevated depressive symptoms; HDL, high-density lipoprotein; HDL-P, high-density lipoprotein particle; IDL-P, intermediate-density lipoprotein particle; LDL, low-density lipoprotein; LDL-P, low-density lipoprotein particle; VLDL-P, very-low-density lipoprotein particle.

Data are expressed as mean (s.d.) or median (interquartile range). P-values were estimated by multivariable linear regression model with continuous measures of lipid and lipoprotein profile as the dependent variable after adjusting for age, sex and race/ethnicity.

^aP-values were estimated using ln-transformed data.