Table 2. Summary of association between PBMC gene expression profile and prognostic marker of outcome in patients after reperfused STEMI (n = 136).
Phenotype | Characteristics of gene expression associations |
|||
---|---|---|---|---|
min. pval | min. qval | FDR ≤ 5% | eta1 | |
late MO (% LV mass) | 3.51 × 10−6 | 0.024 | 398 | 35.7% |
IS (%LV mass) | 2.76 × 10−6 | 0.027 | 2 | 27.1% |
AAR (% LV mass) | 1.44 × 10−5 | 0.125 | 0 | 25.4% |
MSI | 1.59 × 10−5 | 0.150 | 0 | 25.6% |
1min. p:pval minimal p – value, min. q – val: minimal qvalue (i.e. FDR); FDR ≤ 5%: number of associated genes at the default FDR ≤ 5% level of control; estimated percentage of truepositive findings of all 13,486 probes/9,949 genes that could be detected with a very large sample.