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. 2017 Feb 2;10:40. doi: 10.1186/s13045-017-0406-2

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© The Author(s). 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 9 — The meta-analysis of Sirt-1 microarray data identified 28 Sirt-1 globally regulated genes. a Heat map for fold changes of significantly changed genes with adj. p < 0.05 comparing Sirt1 KO to WT or comparing control to treatment or transgenic of Sirt-1. b The top five signatures of Sirt-1 globally regulated genes as revealed by Ingenuity Pathway Analysis (adj. p < 0.05)