Table 1.

Cytokines and chemokines are induced by Bb in glial cells of the CNS and significantly reduced by dexamethasone (when used at concentrations of 150 μM; p < 0.001), as evaluated in culture supernatants after 48 h. Meloxicam had no effect

Rhesus astrocytes			Rhesus microglia			Human oligodendrocytes
Mediator pg/mL	Bb	Bb + dex	Mediator pg/mL	Bb	Bb + dex	Mediator pg/mL	Bb	Bb + dex
IL-1β	24	0	IL-1β	64 ± 10	0	IL-6	141 ± 1.2	65 ± 2.7
IL-2	146	21.8 ± 10	IL-2	268 ± 12	54	IL-8	1145 ± 609	97 ± 2.2
IL-6	27175 ± 2567	596 ± 51	IL-6	92562 ± 2979	1319 ± 77	CCL2	5691 ± 410	1898 ± 96
IL-8	113486 ± 882	1636 ± 40	IL-8	493804 ± 3550	3069 ± 309
IL-10	36	3.72	IL-10	40.45 ± 6.26	17.94
CCL2	76594 ± 1076	2442 ± 260	CCL2	256397 ± 2581	12415 ± 409
CCL3	95.43	0	CCL3	2948 ± 176	136 ± 10
CCL4	25.34	0	CCL4	183.64	0
VEGF	1220 ± 122	0	VEGF	3153 ± 108	941 ± 28
GMCSF	674 ± 20	0	GMCSF	3076 ± 127	501 ± 6.14
			TNF-α	569 ± 45	0