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. 2017 Jan-Mar;20(1):22–27. doi: 10.4103/0971-9784.197823

Table 3.

Comparisons of the cardiac surgery-associated acute kidney injury positive and negative cases using unpaired t-test

Parameters CSA-AKI present (n=49) CSA-AKI absent (n=51) Two-tailed (P)


Mean±SD 95% CI Mean±SD 95% CI
Age (years) 38.53±13.25 34.71-42.34 35.54±11.20 32.39-38.70 0.2268
Weight (kg) 49.59±6.72 47.66-51.52 49.21±6.69 47.33-51.10 0.7798
eGFR (ml/1.73 m2) 68.97±18.73 63.53-74.42 66.56±19.15 61.22-71.90 0.5261
CPB time (min) 103.83±37.6 93.02-114.65 85.66±46.74 72.50-98.82 0.0351
X-clamp (min) 81.44±30.99 72.53-90.35 64.49±40.24 53.16-75.82 0.0206
Intraoperative UO (ml/kg/h) 5.89±1.25 5.53-6.25 6.32±1.17 5.99-6.65 0.0775
POD 1 UO 1.12±0.20 1.06-1.18 1.15±0.23 1.09-1.22 0.3928
POD 2 UO 1.11±0.21 1.065-1.17 1.14±0.22 1.07-1.20 0.5348
POD 3 UO 1.12±0.19 1.07-1.18 1.17±0.25 1.10-1.25 0.2728
POD 4 UO 1.16±0.21 1.10-1.22 1.17±0.27 1.09-1.25 0.8555
POD 5 UO 1.16±0.22 1.10-1.23 1.16±0.20 1.10-1.22 0.9956
Serum creatinine (mg%)
 Preoperative 0.93±0.20 0.87-0.99 1.04±0.19 0.99-1.10 0.0044
 POD 1 1.32±0.36 1.22-1.43 1.08±0.19 1.02-1.13 <0.0001
 POD 2 1.40±0.44 1.28-1.53 1.04±0.21 0.98-1.10 <0.0001
 POD 3 1.40±0.49 1.26-1.54 0.96±0.20 0.90-1.01 <0.0001
 POD 4 1.31±0.39 1.20-1.43 0.93±0.24 0.86-1.00 <0.0001
 POD 5 1.21±0.38 1.10-1.32 0.90±0.16 0.86-0.95 <0.0001
Blood urea (mg%)
Preoperative baseline 31.28±16.47 26.54-36.02 31.31±19.15 25.92-36.70 0.9938
 POD 1 44.75±13.79 40.78-48.72 37.39±13.79 33.52-41.26 0.0088
 POD 2 49.59±13.53 45.70-53.48 37.27±13.13 33.57-40.97 <0.0001
 POD 3 51.89±15.38 47.47-56.32 35.15±13.69 31.30-39.01 <0.0001
 POD 4 48.10±17.10 43.18-53.02 33.54±11.96 30.18-36.91 <0.0001
 POD 5 42.75±17.61 37.69-47.82 32.98±11.40 29.77-36.19 0.0013

eGFR: Estimated glomerular filtration rate, UO: Urine output, CPB: Cardiopulmonary bypass, X-clamp: Aortic cross clamp, SD: Standard deviation, CI: Confidence intervals, POD: Postoperative day, CSA-AKI: Cardiac surgery-associated acute kidney injury