Table 4.
Incidence and relation of cardiac surgery-associated acute kidney injury with different durations of cardiopulmonary bypass and aortic cross clamp time analyzed using ANOVA
| Parameters | CPB time, mean±SD | P | X-clamp time, mean±SD | P | ||||
|---|---|---|---|---|---|---|---|---|
| ≤70 min | 71-140 min | >140 min | ≤60 min | 91-120 min | >120 min | |||
| Age (years) | 31.66±10.30 | 39.57±12.48 | 36.5±12.30 | 0.0196 | 32.0±11.15 | 40.48±11.91 | 37.45±12.90 | 0.0048 |
| Weight (kg) | 49.03±7.23 | 49.18±6.20 | 51.00±7.72 | 0.6282 | 48.13±6.56 | 49.65±6.48 | 52.45±7.43 | 0.1571 |
| Height (cm) | 156.88±5.99 | 158.94±6.18 | 161.57±9.62 | 0.1048 | 157.18±5.48 | 158.82±6.82 | 163.72±9.51 | 0.0179 |
| Base serum creatinine (mg%) | 0.95±0.15 | 1.01±0.21 | 0.97±0.26 | 0.4350 | 0.92±0.16 | 1.03±0.22 | 0.98±0.19 | 0.0468 |
| Baseline eGFR (ml/1.73 m2) | 72.35±19.09 | 65.08±18.30 | 69.89±20.32 | 0.2299 | 72.98±18.95 | 64.10±18.60 | 67.12±17.48 | 0.0901 |
| Baseline blood urea (mg%) | 28.33±12.14 | 33.61±20.83 | 27.28±11.08 | 0.2959 | 27.70±12.59 | 34.55±21.22 | 28.00±12.44 | 0.1634 |
| Intraoperative UO (ml/kg/h) | 7.00±0.62 | 5.97±1.11 | 4.98±1.41 | <0.0001 | 6.75±0.76 | 5.94±1.15 | 4.74±1.47 | <0.0001 |
| CSA-AKI, n (%) | 6 (22.22) | 34 (57.62) | 9 (64.28) | 0.0028* | 12 (32.43) | 30 (57.69) | 7 (63.66) | 0.0159* |
| OR# | Reference | 4.76 | 6.30 | Reference | 2.84 | 3.64 | ||
| 95% CI of OR# | 1.67-13.52 | 1.52-26.09 | 1.17-6.85 | 0.89-14.91 | ||||
*Chi-squared test of independence and #Fisher’s exact test. eGFR: Estimated glomerular filtration rate, UO: Urine output, SD: Standard deviation, CSA-AKI: Cardiac surgery-associated acute kidney injury, OR: Odds ratio, CPB: Cardiopulmonary bypass, X-clamp: Aortic cross clamp, CI: Confidence interval