Figure 4.

(a) MT2A expression at Week 11 (fold-change from Week 0) was determined to be significantly different between treatment groups. Error bars represent standard error (b). However, some dogs showed large variability in MT2A expression (log₂ fold-change) for Week n compared to Week 0 over the course of the feeding trial. Here, the gray lines represent the mean for each treatment group per week. Each colored line represents an individual animal. We emphasize that single-time point analysis of gene response might not reflect variability found in in vivo studies.