Figure 3. Motif scores for the original and modified motifs.

A) We defined 158 motifs covering the variants we were probing. For each motif, we defined modified versions representing treatment by either sialidase 1 or sialidase 2. Two representative motifs are illustrated here. The angled brackets refer to attributes of the immediately following monosaccharide. (See supplementary information for details on the motif language and the motifs.) B) For each of the 158 motifs we calculated a motif score from glycan array data (obtained from the Consortium for Functional Glycomics) for each lectin, using both the original and modified motifs. We then calculated the differences between the modified and original motif scores, indicated by ΔSialidase1 andΔSialidase2.