Skip to main content
. 2017 Feb 3;7:39527. doi: 10.1038/srep39527

Table 2. Results of single and multiple logistic regression analyses of DEGs in OSKM + miR-29b-iPSC based on logFPKM_iPSC, K36, K4, and K27 signals.

  Crude OR (95%CI) Adj. OR (95%CI) P (Wald’s test) P (LR-test)
DEGs up-regulated by miR-29b
 logFPKM_iPSC (cont. var.) 0.19 (0.17, 0.21) 0.16 (0.13, 0.18) <0.001 <0.001
 GSE12241_ES_H3K36me3: 1 vs 0 0.48 (0.37, 0.62) 1.34 (1.02, 1.76) 0.036 0.042
 GSE12241_ES_H3K4me3: 1 vs 0 0.81 (0.72, 0.91) 1.53 (1.34, 1.75) <0.001 <0.001
 GSE12241_ES_H3K27me3: 1 vs 0 3.14 (2.59, 3.81) 1.60 (1.31, 1.97) <0.001 <0.001
DEGs down-regulated by miR-29b
 logFPKM_iPSC (cont. var.) 0.77 (0.65, 0.92) 0.98 (0.82, 1.16) 0.783 0.783
 GSE12241_ES_H3K36me3: 1 vs 0 0.16 (0.07, 0.39) 0.22 (0.09, 0.54) <0.001 <0.001
 GSE12241_ES_H3K4me3: 1 vs 0 0.56 (0.44, 0.72) 0.61 (0.47, 0.79) <0.001 <0.001
 GSE12241_ES_H3K27me3: 1 vs 0 2.67 (1.82, 3.93) 2.74 (1.84, 4.10) <0.001 <0.001