Figure 6. The increased CD8⁺ T cell functional avidity induced by VACV boost was not associated with cytokine profile of CD4⁺ T cells, memory phenotype and poly-functionality of antigen-specific CD8⁺ T cells.

To explore the possible association of the functional avidity with other important immune factors, the cytokines profile of CD4⁺ T cells (A), the proportion of central and effector memory phenotypes (B to D), and poly-functionality of antigen-specific CD8⁺ T cells (E,F) from different vaccination regimens was assessed.