Table 1. Multiple Sry copies are present in M. minutoides and M. mattheyi.
Clone # | Haplotype | Sry DNA sequence variation | SRY protein sequence variation |
---|---|---|---|
M. minutoides | |||
1 | a | c.514_534del | p.(E170_Q176del) in the polyQ domain |
2 | a | c.514_534del | p.(E170_Q176del) in the polyQ domain |
3 | b | c.[352A > G; 613_615del] | p.(T118A) in the bridge domain |
4 | c | c.[51T > C; 410A > G; 573T > C] | p.(D137G) in the polyQ domain |
5 | d | Same as the consensus | Same as the consensus |
6 | e | c.316A > G | p.(R106G) in the bridge domain |
7a | d | Same as the consensus | Same as the consensus |
8 | d | Same as the consensus | Same as the consensus |
M. mattheyi | |||
1 | a | c.971_973del | Same as the consensus |
2 | b | c.562_564del | p.(Q188del) in the polyQ domain |
3 | c | c.503_574del | p.(Q172_Q195del) in the polyQ domain |
4a | d | Same as the consensus | Same as the consensus |
5 | b | c.562_564del | p.(Q188del) in the polyQ domain |
6 | e | c.503A > G | p.(H168R) in the polyQ domain |
7 | f | c.787C > T | Same as the consensus |
8 | g | c.451C > T | p.(Q150*); almost complete truncation of the polyQ domain |
aReference clones used in cross-species sequence comparisons and subsequent experimental analyses.