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. 2016 Jan 7;17(2):202–219. doi: 10.15252/embr.201540795

Figure 9. Model of exomer assembly at the trans‐Golgi network (TGN).

Figure 9

  1. Dual role of ChAPs in formation of the exomer complexes at the TGN. ChAPs differently stabilize Chs5 at the trans‐Golgi network TGN and also have variable specificities for different cargoes.
  2. Model of the dynamic assembly of the exomer cargo adaptor. (1) Chs5 and Arf1 initiate the complex formation. (2) Chs6 recruitment promotes assembly of the exomer intermediate. (3) Bch1 enhances stabilization of the exomer tetramer at the TGN membrane. (4) Arf1, exomer tetramer, and the cargoes act together as the primer for the exomer coat mediated vesicle budding.