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Rat PK parameters
| Rat PK study (5 mg/kg SC) | T1/2 | AUC | CL/F |
|---|---|---|---|
| Day | μg × day/ml | ml/h/kg | |
| mAbW.IgG1 | 12 ± 3 | 1050 ± 216 | 0.204 ± 0.044 |
| mAbW.SEFL1.1 | 12 ± 1 | 903 ± 126 | 0.234 ± 0.035 |
| mAbW.SEFL1.2 | 12 ± 1 | 790 ± 55 | 0.265 ± 0.018 |
| mAbW.SEFL1.3 | 10 ± 3 | 866 ± 141 | 0.245 ± 0.041 |
| mAbW.SEFL2.0 | 5 ± 3 | 332 ± 56 | 0.641 ± 0.120 |
| mAbW.IgG2 | 19 ± 3 | 1477 ± 266 | 0.144 ± 0.027 |
