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Direct binding of mAbs to cynomolgus monkey granulocytes was assessed by flow cytometry. SEFL mAbW variants (mAbW.SEFL1.1, mAbW.SEFL2.0, mAbW.SEFL2.1, and mAbW.SEFL2.2), the IgG2 control mAbV.IgG2, and the IgG1 control mAbW.IgG1 were tested for direct binding to cynomolgus monkey granulocytes.
