FIGURE 8.
Localization of KRIT1FL is driven by ICAP1. CHO cells co-overexpressing GFP or GFP-tagged KRIT1 constructs and DsRed-tagged ICAP1 constructs were plated on fibronectin, fixed 24 h later, and stained with DAPI to identify nuclei. A and B, percentage nuclear fluorescence compared with the integrated fluorescence intensity of the entire cell for GFP (A) and DsRed (B) was calculated. Boxes, 25th through 50th and 50th through 75th percentile; whiskers, 5th through 95th percentile (n = 47–103 cells from three independent experiments). *, p ≤ 0.0001 as determined by a one-way ANOVA with Tukey's correction for multiple tests.