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. 2004 Dec;72(12):6773–6779. doi: 10.1128/IAI.72.12.6773-6779.2004

FIG. 5.

FIG. 5.

cag+ H. pylori induced more severe downregulation of CXCR1 and CXCR2 mRNAs in purified human neutrophils than cag deletion H. pylori. Neutrophils incubated in RPMI for 0.5 and 3 h strongly expressed CXCR1 and CXCR2 mRNAs (lanes 1 and 4). H. pylori downregulated CXCR1 and CXCR2 mRNAs in neutrophils 3 h after incubation (lanes 5 and 6). CXCR1 and CXCR2 mRNAs were not downregulated 0.5 h after coincubation with H. pylori (lanes 2 and 3). The H. pylori cag+ strain (lane 5) downregulated CXCR1 and CXCR2 mRNAs significantly more strongly than the cag deletion mutant (lane 6).