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. 2017 Feb 3;7:41864. doi: 10.1038/srep41864

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Copyright © 2017, The Author(s)

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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Huh7.5 cells were infected with DENV-1/FGA/89 (A), DENV-2/ICC265 (B), DENV-3/5532 (C) and DENV-4/TVP360 (D) and treated with naringenin (250 μM) 1.5 h before infection, during infection, after infection, and during and after infection. As a control, cells were treated with IFN-α 2A (200 IU/mL) after DENV infection. The data represent the mean ± SEM of three independent experiments. One-way ANOVA and Dunnett’s test for multiple comparisons (*p < 0.05 compared to DENV control).