Figure 2. Partial bile duct ligation results in liver remodelling and collagen deposition in occluded lobes.

Adult mice were subjected to partial bile duct ligation and sacrificed after 90 days. Control livers from sham operated mice (Ai) and occluded pBDL livers (Aii) were fixed, sectioned and stained with Hematoxylin & Eosin for histological architecture and Lilly’s trichrome (Bi & ii) staining collagen (blue), nuclei (black) and cytoplasm (red). Bile duct (bd), portal vein (pv), biliary hyperplasia (bh), ductular reaction (dr), (n = 3 both groups).