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. 2017 Feb 3;37(1):BSR20160479. doi: 10.1042/BSR20160479

Figure 3. Hypoxia increases lipid oxidation via mTORC1 signalling in lymphocytes.

Figure 3

(A) A schematic model showing the signalling of lipid oxidation. Atgl, Pparα and Cpt1-α are important genes involved in lipid β-oxidation. (B–D) Real-time PCR results showed that mRNA levels of lipid oxidation genes, including Atgl (B), Pparα (C) and Cpt1-α (D) were increased in hypoxia. TSC1 knockdown decreases these gene expressions in both normoxia and hypoxia. Results are averages of three independent experiments. Data represent mean ± S.E.M.; *P<0.05, **P<0.01 and ***P<0.001.