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. 2016 Nov 24;21(47):30406. doi: 10.2807/1560-7917.ES.2016.21.47.30406

Table 4. Factors associated with higher vaccine hesitancy among general practitioners', ordered logistic regressions, weighted data, France, April to July 2014 (n = 1,427a).

Univariable regression Multivariable regression
Odds ratio
(95% CI)
Adjusted odds ratio
(95% CI)
Stratification variables
Sex (ref. Male)
Female 0.92 (0.69–1.23) 0.94 (0.63–1.38)
Age in years (ref. < 50)
50–58 1.12 (0.79–1.59) 0.67 (0.44–1.03)
> 58 1.69 (1.19–2.38) 1.00 (0.63–1.61)
Density of GP’s municipality of practice (ref. < −19.3% of national average)
Between −19.3% and  +17.7% of national average 0.77 (0.55–1.07) 0.76 (0.52–1.11)
>  +17.7% of national average 1.09 (0.76–1.58) 1.09 (0.72–1.66)
2012 workload (ref. < 3,067 consultations/visits)
3,067–6,028 consultations/visits 0.39 (0.28–0.55) 0.69 (0.46–1.04)
> 6,028 consultations/visits 0.50 (0.35–0.72) 0.91 (0.58–1.45)
Professional characteristics
Practice (ref. Solo)
Group 0.59 (0.45–0.79) 1.10 (0.77–1.57)
Coordinator in a retirement home (ref. No)
Yes 0.67 (0.35–1.28) 0.92 (0.45–1.89)
Work in a healthcare institution (ref. No)
Yes 0.67 (0.44–1.02) 0.74 (0.45–1.21)
Occasional practice of alternative medicineb (ref. No)
Yes 5.68 (4.04–7.98) 2.89 (1.94–4.31)
Continuing medical education on infectious diseases and vaccination in 2013 (ref. No)
Yes 0.65 (0.49–0.88) 0.94 (0.67–1.32)
Characteristics of practice population
Proportion of patients aged under 16 (0–50%) 0.97 (0.95–0.99) 0.99 (0.96–1.01)
Experience related to vaccination
Number of different vaccine-preventable diseases among the GP’s patients (0–5)c 0.70 (0.62–0.80) 0.78 (0.67–0.90)
Has had patients with a serious health problem potentially related to vaccination (ref. No)
Yes 2.30 (1.64–3.22) 1.82 (1.23–2.68)
Personal vaccinations
Vaccination against 2013–2014 seasonal influenza (ref. Yes)
No 4.48 (3.34–6.01) 2.51 (1.78–3.54)
Last diphtheria-tetanus-polio (dTPolio) booster (ref. <10 years ago)
10–20 years ago 2.37 (1.63–3.43) 1.58 (1.02–2.46)
>20 years ago 6.60 (3.60–12.08) 2.23 (1.16–4.26)
Vaccination against hepatitis B (ref. Yes, 3 or more doses)
Yes, fewer than 3 doses 2.76 (1.55–4.89) 1.36 (0.72–2.57)
No, or don't remember 4.22 (2.87–6.21) 1.55 (0.94–2.55)
Nagelkerke R2 0.21

CI: confidence interval; GP: general practitioner.

a 155 GPSs were excluded because of missing values about the characteristics of their practice population (n = 148) or about their vaccine hesitancy (n = 7).

b Homoeopathy and/or acupuncture.

c Five vaccine-preventable diseases were mentioned in the questionnaire: measles, acute or recently diagnosed chronic hepatitis B, bacterial meningitis, cervical cancer and complicated seasonal influenza requiring hospitalisation.